Fluorescence-Based Blood Coagulation Assay Device for Measuring Activated Partial Thromboplastin Time
نویسندگان
چکیده
منابع مشابه
Fluorescence-based blood coagulation assay device for measuring activated partial thromboplastin time.
The measurement of blood clotting time is important in a range of clinical applications such as assessing coagulation disorders and controlling the effect of various anticoagulant drug therapies. Clotting time tests essentially measure the onset of clot formation which results from the formation of fibrin fibers in the blood sample. However, such assays are inherently imprecise due to the highl...
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‘ITHE partial thromboplastin time assay (PTT) as developed by Langdell et al. (1) has proved to be a very usef ul test for studying the coagulatioll mechanism silice it C 11 reveal tile al)SellCe of any factor except Factor VII and platelets. lnder rigorously cOlitrolled COll(litiOlIS, the reproducibility of tile test is satisfactory. However, any change ill tile surface of the svl’inge, test t...
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The pathological activated partial thromboplastin time test is a data that we can find in all clinical laboratories routinely. The hemato-coagulative clinical case here reported aims to point out how the laboratory can provide a correct diagnosis by methodological rational setting and, consequently, carry out an appropriate therapy, or reassure the patient that the pathological data will not ca...
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INTRODUCTION The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differences between aPTT reagents stored in a dried format to select the most suitable formulations to be used for the development of point-of-care diagnost...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2011
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac102436v